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New synthetic organic compounds of ceramide type useful in cosmetic formulations to restore a protective skin barrier damaged by ageing or other external factors such as UV or chemical products

机译:新的神经酰胺类合成有机化合物可用于化妆品配方中,以恢复因老化或其他外部因素(例如紫外线或化学产品)而损坏的保护性皮肤屏障

摘要

The synthetic ceramide-type compounds are similar in structure to natural ceramides, possessing long chain alkyl groups and hydroxyl groups ; phosphoric or sulfuric groups may also be introduced to increase penetration of the permeable barrier. The compounds are of the general formula (I): m, n = 1 - 3; k, l = 1 - 2; j = 0 or 1; A1, A2, A3 = H or a structure (II):- (M, M1, M2 = alkaline earth metals or a notrogenous base, and L = an alkaline earth metal); R = a group of structure (III):- (B = Me, in position 5,7 or 8 ; m = 1 - 3; and D = -CH3-CH(CH3) or -CH=C(CH3)). An Independent claim is also included for preparation of the compounds.
机译:合成的神经酰胺类化合物的结构与天然神经酰胺相似,具有长链烷基和羟基。还可引入磷酸或硫酸基团以增加渗透性屏障的渗透。所述化合物具有通式(I):m,n = 1-3;和n = 1-3。 k,l = 1-2; j = 0或1; A 1,A 2,A 3 = H或结构(II):-(M,M 1,M 2 =碱土金属或非金属碱,L =碱金属土金属); R =一组结构(III):-(B = Me,在5,7或8位; m = 1-3;和D = -CH 3 -CH(CH 3)或-CH = C(CH 3))。还包括用于制备化合物的独立权利要求。

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