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Substituted 9H-pyridino2,3-b indole and 9H-pyrimidino4,5-b indole derivatives: selective neuropeptide Y receptor ligands

机译:取代9H-吡啶并[2,3-b]吲哚和9H-嘧啶并[4,5-b]吲哚衍生物:选择性神经肽Y受体配体

摘要

Disclosed are compounds of the formula: chemistry chemdraw filechemistry mol file;wherein Ar, R1, W and X are substituents as defined herein, ;which compounds are effective neuropeptide Y1 receptor antagonists, and are therefore useful in the treatment of a wide variety of clinical conditions which are characterized by the presence of an excess of neuropeptide Y.
机译:公开了下式的化合物: <图像文件=“ US20010031758A1-20011018-C00001.GIF” he =“ 73.45485” imgContent =“ undefined” imgFormat =“ GIF” wi =“ 155.04615” /> 化学chemdraw文件 化学mol文件< / ExternalFileRef> ;其中Ar,R 1 ,W和X是本文定义的取代基;这些化合物是有效的神经肽Y1受体拮抗剂,因此可用于治疗多种以过量的神经肽Y为特征的各种临床疾病。

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