Pegylated drug complexed with bioadhesive polymer suitable for drug delivery and methods relating thereto

摘要

PEGylated drugs complexed with bioadhesive polymers, wherein the PEGylated drugs comprise a polyethylene glycol covalently bonded to the drugs are disclosed. The PEGylated drug/bioadhesive polyner complex and compositions thereof may be topically administered to body fluids or mucosal tissues. Methods of administering the PEGylated drug/bioadhesive polymer complex and compositions thereof to an animal are also disclosed.