Microspheric embolic materials having a dual structure of poly(vinyl acetate) core and poly(vinyl alcohol) shell and method for preparing the same

摘要

A method for separating poly(vinyl acetate) particles having various particle sizes, which have been prepared by suspension polymerization of vinyl acetate monomers, into respective microspheric poly(vinyl acetate) particles with uniform particle size distribution by the use of inorganic salt as a dispersing and antistatic agent, a method for preparing the microspheric embolic particles of a dual structure consisting of poly(vinyl acetate) core/poly(vinyl alcohol) shell by suspending the separated poly(vinyl acetate) particles into an aqueous alkali solution and subjecting the suspended particles to a heterogeneous surface saponification and the microspheric embolic particles prepared.