;wherein R1 and R10 are each independently of the other lower alkoxycarbonyl; either R2, R3 and R4 are each independently of the other C1-C4alkyl and R7, R8 and R9 are each selected from hydrogen and C1-C4alkyl, with not more than 2 of the radicals being hydrogen; or R7, R8 and R9 are each independently of the other C1-C4alkyl and R2, R3 and R4 are each selected from hydrogen and C1-C4alkyl, with 1 or 2 of the radicals being hydrogen; R5 is phenyl or cyclohexyl; and R6 is phenyl or cyanophenyl; or salts thereof; those compounds are inhibitors of retroviral aspartate proteases and are effective, for example, against HIV."/>
公开/公告号US6225345B1
专利类型
公开/公告日2001-05-01
原文格式PDF
申请/专利权人 NOVARTIS AG;
申请/专利号US19980068876
申请日1998-05-21
分类号A61K312/70;C07C2711/00;C07C2690/40;
国家 US
入库时间 2022-08-22 01:04:27