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Crystalline (R- (RR *, R ▲ *)) of Form III III-2- (4-fluorophenyl) -β, δ-dihydroxy-5- (1-methyl-ethyl) -3-Phenyl-4-((phenylamino) carbonyl) -1H-pyrrole-1-heptanoic acid hemicalcium salt (atorvastatin)
Crystalline (R- (RR *, R ▲ *)) of Form III III-2- (4-fluorophenyl) -β, δ-dihydroxy-5- (1-methyl-ethyl) -3-Phenyl-4-((phenylamino) carbonyl) -1H-pyrrole-1-heptanoic acid hemicalcium salt (atorvastatin)
A novel crystalline form of [(R-(R*,R*)]-2-(4-fluorophenyl)- beta , delta -dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium salt designated Form III is characterized by its X-ray powder diffraction and/or solid state NMR is described, as well as methods for the preparation and pharmaceutical composition of the same, which is useful as an agent for treating hyperlipidemia and hypercholesterolemia.
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