首页> 外国专利> METHOD FOR PRODUCING N-ACYLATED beta-AMINO ACID HAVING CONCENTRATED ENANTIOMER, METHOD FOR PRODUCING beta-AMINO ACID BY PROTECTIVE GROUP SEPARATION AND USE THEREOF

METHOD FOR PRODUCING N-ACYLATED beta-AMINO ACID HAVING CONCENTRATED ENANTIOMER, METHOD FOR PRODUCING beta-AMINO ACID BY PROTECTIVE GROUP SEPARATION AND USE THEREOF

机译:具有浓缩对映体的N-酰化β-氨基酸的制备方法,保护基分离法制备β-氨基酸的方法及其用途

摘要

PROBLEM TO BE SOLVED: To provide a method for a -amino acid production, which is excellently usable on an industrial scale, eventually, economically excellent, for example, excellent from the viewpoint of ecology, with which a -amino acid is produced under low hydrogen pressure in a shorter hydrogenation time. SOLUTION: An N-acylated 5-amino acid having concentrated enantiomer is obtained by carrying out an enantiomer-selective catalytic hydrogenation of a prochiral N-acylated Z-5-aminoacrylic acid in the presence of a compound represented by general formula (I) [R1 , R2 , R3 and R4 are each described in the specification] in a polar solvent.
机译:解决的问题:提供一种用于生产α-氨基酸的方法,该方法在工业规模上极好使用,最终在经济上是优异的,例如,从生态学的角度来看,在低温下生产α-氨基酸是极好的。氢气压力在较短的氢化时间内。解决方案:通过在通式(I)表示的化合物存在下,对前手性N-酰化Z-5-氨基丙烯酸进行对映体选择性催化氢化,可以得到具有浓缩对映异构体的N-酰化5-氨基酸。 R 1,R 2,R 3和R 4在极性溶剂中分别在说明书中描述。

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