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METHOD FOR SYNTHESIZING 2-THIOURIDINE ANALOG
METHOD FOR SYNTHESIZING 2-THIOURIDINE ANALOG
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机译:2-硫代鸟嘌呤类似物的合成方法
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摘要
PROBLEM TO BE SOLVED: To provide a method for efficiently synthesizing a 2-thiouridine analog in large quantities from inexpensive compounds.;SOLUTION: This method for synthesizing a 2-thiouridine analog is characterized by comprising the respective protective steps 10, 11 and 12 of introducing respective protective groups onto the hydroxy group at the 3'-position, the hydroxy group at the 5'-position, and the carbonyl group at the 4-position of an uridine analog, the functional group substitution step 13 of converting the carbonyl group at the 2-position of the uridine analog into a thiocarbonyl group, and the respective deprotecting steps 14 and 8 of eliminating the protective groups introduced in the protective steps after the functional group substitution.;COPYRIGHT: (C)2002,JPO
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