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Quinoline and quinoxaline compounds that inhibit platelet-derived growth factor and / or tyrosine kinase P56

机译:抑制血小板衍生生长因子和/或酪氨酸激酶P56的喹啉和喹喔啉化合物

摘要

This invention is directed to quinoline/quinoxaline compounds which inhibit platelet-derived growth factor or p56lck tyrosine kinase activity, to pharmaceutical compositions comprising these compounds, and to the use of these compounds for treating a patient suffering from or subject to disorders/conditions involving cellular differentiation, proliferation, extracellular matrix production or mediator release and/or T cell activation and proliferation.
机译:本发明涉及抑制血小板衍生的生长因子或p56 lck酪氨酸激酶活性的喹啉/喹喔啉化合物,包含这些化合物的药物组合物,以及这些化合物在治疗患有疾病或遭受疾病/涉及细胞分化,增殖,细胞外基质产生或介质释放和/或T细胞活化和增殖的疾病。

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