MEN1, main Nin polypeptide, and its use is a gene associated with type 1 multiple endocrine tumor

摘要

(57) [summary] The present invention relates to the discovery of the tumor suppressor gene novel related to type 1 multiple endocrine tumors. This gene product is a Menin this gene, and has been referred to as the MEN1. Mutations associated with corresponding genes and the absence of this protein has been identified in individuals suffering from type 1 multiple endocrine tumors. And have utility for diagnosis and identification of the markers for multiple endocrine tumors type 1 is for gene therapy.