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METHOD FOR PREPARING DIRECTLY COMPRESSIBLE BETA- CYCLODEXTRIN AND DIRECTLY COMPRESSIBLE BETA- CYCLODEXTRIN PREPARED THEREBY
METHOD FOR PREPARING DIRECTLY COMPRESSIBLE BETA- CYCLODEXTRIN AND DIRECTLY COMPRESSIBLE BETA- CYCLODEXTRIN PREPARED THEREBY
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机译:制备直接可压缩的β-环糊精的方法及由此制备的直接可压缩的β-环糊精
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摘要
PROBLEM TO BE SOLVED: To provide a method for preparing a beta-cyclodextrin high in compressibility and in long-term stability and to provide the beta-cyclodextrin prepared thereby.;SOLUTION: The method comprises a process wherein a hydrated beta- cyclodextrin is dehydrated until its water content occupies 6 mass%, preferably less than 4 mass%, and still preferably 2 mass% or less, and a process wherein the beta-cyclodextrin is compulsorily rehydrated until its water content occupies more than 10 mass%, preferably more than 12 mass%, and still preferably 13 mass% or more. The beta-cyclodextrin prepared by this method is beyond 70 N in compressibility in a C test.;COPYRIGHT: (C)2002,JPO
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机译:解决的问题:提供一种制备可压缩性和长期稳定性高的β-环糊精的方法,并提供由此制备的β-环糊精。解决方案:该方法包括其中将水合的β-环糊精脱水的方法。直至其水含量占6质量%,优选小于4质量%,并且仍优选为2质量%或更小,以及强制将β-环糊精再水化直到其水含量占10质量%以上,优选大于1的方法。 12质量%,更优选13质量%以上。用这种方法制备的β-环糊精在C试验中的可压缩性超过70 N 。;版权所有:(C)2002,JPO
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