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SREBP-2 GENE EXPRESSION PROMOTING AGENT

机译:SREBP-2基因表达促进剂

摘要

PROBLEM TO BE SOLVED: To obtain an SREBP-2 gene expression promoting agent capable of significantly promoting the expression of SREBP-2 gene deeply participating in the control of a fatty acid metabolism-relating enzyme and a fatty acid synthesis enzyme in addition to the biosynthesis and uptake of cholesterol and, accordingly, useful as an agent for depressing neutral fat level in blood. SOLUTION: This SREBP-2 gene expression promoting agent contains a compound expressed by general formula (1) (R is an organic group; X is CH2CH2 or CH=CH; and M is H, an alkyl or a physiologically permissible cationic group) or its lactone as an active component.
机译:要解决的问题:获得一种SREBP-2基因表达促进剂,其能够显着促进除生物合成外深深参与脂肪酸代谢相关酶和脂肪酸合成酶的控制的SREBP-2基因的表达。胆固醇的吸收,因此可用作降低血液中中性脂肪水平的药物。 SOLUTION:该SREBP-2基因表达促进剂包含通式(1)表示的化合物(R为有机基团; X为CH2CH2或CH = CH; M为H,烷基或生理上允许的阳离子基团)或其内酯为有效成分。

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