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Aerogels and other coatings as collection media and matrix supports for MALDI-MS applications
Aerogels and other coatings as collection media and matrix supports for MALDI-MS applications
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机译:气凝胶和其他涂料作为MALDI-MS应用的收集介质和基质载体
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摘要
Techniques to modify and apply aerogel coatings are described, including the application of spray-coated aerogels. The approach eliminates several of the wet chemical techniques previously needed for processes such as MALDI processing, and simplifies the automation of processes such as continuous monitoring in a sensor based format. With respect to MALDI processing, the preferred embodiment uses an acid-doped silica aerogel coated tape as the collection media as well as the matrix support. Although aerogels are disclosed as a preferred matrix material, other materials may alternatively be used, including linoleic acids, oleic acids, PEG (polyelthylene glycol), preferably in tape format.
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