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Method and system for improving the effectiveness of medical stents by the application of gas cluster ion beam technology

机译:应用气体团簇离子束技术提高医用支架有效性的方法和系统

摘要

Numerous studies suggest that the current popular designs of coronary stents are functionally equivalent and suffer a 16 to 22 percent rate of restenosis. Although the use of coronary stents is growing, the benefits of their use remain controversial in certain clinical situations or indications due to their potential complications. The application of gas cluster ion beam (GCIB) surface modification such as smoothing or cleaning appears to reduce these complications and lead to genuine cost savings and an improvement in patient quality of life. The present invention is directed to the use of GCIB surface modification to overcome prior problems of thrombosis and restenosis. The atomic level surface smoothing of stents utilizing GCIB substantially reduces undesirable surface micro-roughness in medical coronary stents.
机译:大量研究表明,目前流行的冠状动脉支架设计在功能上是等效的,再狭窄率达到16%至22%。尽管冠状动脉支架的使用正在增长,但由于其潜在的并发症,在某些临床情况或适应症中使用冠状动脉支架的益处仍存在争议。气体团簇离子束(GCIB)表面修饰(如平滑或清洁)的应用似乎减少了这些并发症,并真正节省了成本,并改善了患者的生活质量。本发明涉及使用GCIB表面改性来克服血栓形成和再狭窄的先有问题。利用GCIB进行支架的原子级表面光滑处理,可大大降低医用冠状动脉支架中不良的表面微观粗糙度。

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