Process for producing carboxylic acid isomer using Nocardia diaphanozonaria or Saccharopolyspora hirsuta

摘要

The present invention provides a process for producing a carboxylic acid isomer B represented by the general formula (2): ;(wherein, L is a C₆ to C₁₄ aryl group which may optionally been substituted, C₄ to C₁₂ heteroaryl group which may optionally been substituted, C₆ to C₁₄ aryloxy group which may optionally been substituted or C₄ to C₁₂ heteroaryloxy group which may optionally been substituted, and M is an C₁ to C₃ alkyl group.), which comprises:;allowing a carboxylic acid isomer A represented by the general formula (1): ; (wherein, L and M have meanings as defined above.) to contact with a microbiological material having an ability to convert the carboxylic acid isomer A(1) into the carboxylic acid isomer B(2), and the like. According to the present invention, the carboxylic acid isomer B(2) useful as an intermediate of medicines, agricultural chemicals and like can be produced efficiently.