Endoglycan: a novel protein having selectin ligand and chemokine presentation activity

摘要

Nucleic acid compositions encoding novel endoglycan proteins, as well as the novel endoglycan proteins, are provided. Also provided are methods of producing the subject nucleic acid and protein compositions. The subject polypeptide and nucleic acid compositions find use in a variety of applications, including diagnostic and therapeutic agent screening applications, as well as in treatment therapies for disease conditions associated with endoglycan activity. In particular, methods of treating diseases associated with endoglycan selectin binding activity and/or chemokine presenting activity are provided, where such diseases include inflammation and the like.