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Methods for discovery of vasoactive compounds for the nitric oxide-cyclic GMP signal pathway
Methods for discovery of vasoactive compounds for the nitric oxide-cyclic GMP signal pathway
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机译:一氧化氮-环GMP信号通路的血管活性化合物的发现方法
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摘要
The invention features methods for assaying compounds that affect the activation of a cell. The methods include measurement of cell activation, G protein-coupled receptor phosphorylation, or phosphorylation of proteins associated with the G-protein-coupled receptor, in a system comprising G protein-coupled receptor-bearing cells, or preparations thereof, cyclic GMP, or analogs thereof, and cyclic GMP-dependent protein kinase.
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