(of one or More Fragments of Antibodies covalently coupled to one or more Polymer molecules not ProteinA composition that includes and the use thereof for the preparation of a Medicament for treating an inflammatory disorder in a Mammal.

摘要

Describes a conjugate consisting essentially of one or More Fragments of Antibody covalently attached to one or more Polymer Molecules noproteico,The apparent size of the conjugate is at least approximately 500 KD, and unacomposi tion that understands.The conjugate exhibits a vidamedia improvedAs a best time of permanence and / or clearance in circulation Speed in comparison with the parental Antibody fragment sinderivar.Also describes the use of conjugated Polymer fragment anti IL - 8 where the apparent size of the conjugate is greater than 500kd for the treatment of inflammatory disorders.