Stabilized Pharmaceutical composition containing a drug component which comprises a component that includes an ace inhibitor Drugs,Unestabilizador Agent and a minimization of hydrolysis, tablet containing it and Process for Stabilizing a drug

摘要

Compositions containing ACE Inhibitor, Stabilized by the presence of magnesium oxide.Preferably, the inhibitor of angiotensin enzimaconversora quinapril, is protected from certain forms of degradation, cyclization, hydrolysis, oxidative discoloration, etc.When seprepara in a Pharmaceutical composition consisting essentially of magnesium oxide as Stabilizing Agent.The presence of magnesium oxide also provides favourable conditions for processing during the production of compositions containing ACE Inhibitor,Especially procesamientomediante in wet granulation.They also contain an agent that minimizes hydrolysis, The Ace Inhibitor, a diuretic, as a saccharide, fosfatodicu00e1lcico or fillers.It includes the tablet containing Said Composition and Process for Stabilizing such Drugs, which takes place in the compositions of the presentWhich comprises contacting the drug with oxide agnesio Agent M and a minimization of hydrolysis. The Ace inhibitor is formulageneral (i).