Retrovirus Packaging cell line anfotropico, Process for its production, and Process for the production of a retroviral vector using the same.

摘要

Anfotropico retroviral Packaging cell line that contains Functional genes gag, Pol and env integrated in the genome.Where the expression of gag and Pol genes is regulated independently of the expression of env genesWhere thegenome of this Cell Line contains one or two genes envfuncionalmente assets to obtain a degree of Retroviral vectors for at least 107 Colony Forming Units /Ml grown Cell supernatants, Process for their production, virus Replication incompetent retroviral Vector and Process for its production.