Lipl46 substantially isolated Purified polypeptide, polynucleotide, expression vector, host Cell, method for producing the polypeptide, antibodyPharmaceutical composition for Inducing an immune response to pathogenic spirochete, use of said polypeptide for Manufacturing d

摘要

2. Basically pure polypeptide lipl 46, the amino acid sequence of which is shown in SEC ID NS 2; the separated polysribose, vector deepening, host cell, method of producing this polypeptide, antibody, crystal, to induce immune response to pathogenic spirulina, The method of using this peptide to make drugs, identify compounds related to difluorodipeptide, and detect deuna is a kind of pathogenic flame retardant, a method of detecting antibody of this peptide and a practical screening equipment of this peptide,The nucleic acid of this polypeptide and the antibody of this polypeptide. The external demembrant protein associated with Leptospira's pathogenic strain was identified as lipid 46 because of Leptospira's lipoproteins and because of the migration and binding of the separated peptides, its molecular weight in the desulfurized deacrylonitrile gel was KWD 46. Polynucleoside 46 encoded by fat and antibody linked to protein are effective methods for the diagnosis of leptospirosis. In addition, lipid 46 can be used for immunization as a vaccine for parasitic diseases related to helix.