The use of non steroidal anti-inflammatory compounds for preparing Medicines,Non steroidal compounds which are suitable for this job and lospreparados Pharmaceuticals containing these compounds

摘要

A drug with an anti-inflammatory effect is prepared using non steroidal compounds in response to a common formula (1), wherein R1 and R2 are the same or different, representing a hydrogen atom, a tar group 1-5, or together with a C atom in the chain, R3 represents a group of C1-5 partially or completely fluorinated tar; a represents a group of formula (6), where (dotted line refers to ligation),R4 represents a hydrogen atom, a C1-5 tar group, a C1-10 ACIO group, a c3-10 massive skeleton, a c2-5 cyanopropyl compound, a substituted or substituted alilo c3-10 group, a substituted or abandoned propylene c3-10 group, an ungrupo alcoxicologio c2-5, A group of C1-5 tar is partially or completely replaced by fluorinated atoms; r5-r8 is the same or different, and is selected as a group composed of hydrogen atoms, halogenated atoms and alcoxi C1-5, R4 and R5. Together, it also represents an overall aperiodic queen ring with 5-7 members. OxygenIt may eventually contain at least another heteroatom composed of oxygen, nitro and sulfur; B represents a carbon group or a CH2 group; and AR represents a ring system selected from some recipe groups (2) to (5).where the residues X3a, X3b, X4, X6, X7 (in the partial formulas (2) and (3)) and Y4, Y5, Y7, Y8 (in the partial formulas (4) and (5)) are equal or different and are chosen from hydrogen atoms, C1-5 allyl groups, partially or fully fluorinated C1-5 alkyl groups, and furthermore residues X4, X6, X7 (of the partial formulas (2) and (3)) or the residues Y5, Y7, Y8 (in the partial formulas (4) and (5)) are chosen from halogen atoms, hydroxyl groups, C1-5 alkoxy groups or C1-5 alkanoyloxy groups, and, for the case in that B represents a CH2 group, physiologically acceptable salts are also used,The general formula compound (1) is formed by the total amount of acid. Of pharmaceutical preparations