THE USE OF OPTICALLY PURE (+) NORCISAPRIDE FOR TREATING GASTRO-ESOPHAGEAL REFLUX DISEASE

摘要

Compositions employing and methods utilizing the optically pure (+) isomer of norcisapride is disclosed. The compound has surprisingly been found to be a potent drug for the treatment of disorders of the central nervous system. The compound, (+) norcisapride, has also been found to be a potent antiemetic agent. Finally, the (+) isomer of norcisapride also avoids certain adverse side effects and certain adverse drug interactions, The compound is further useful for treating gastro-intestinal motility dysfunction, gastro-esophageal reflux disease, dyspepsia, gastroparesis, intestinal pseudo-obstruction. It has a prokinetic effect. 24 claims