Compound, use of the same, process to prepare a compound, pharmaceutical composition, and methods to treat a disease in an animal in which the activity of cysteine protease contributes to the pathology and / or symptomatology of the disease, and to treat a disease in an animal in which the activity cathepsin s contributes to the pathology and / or symptom of the disease

摘要

"COMPOUND, USE OF THE SAME, PROCESS TO PREPARE A COMPOUND, PHARMACEUTICAL COMPOSITION, AND METHODS TO TREAT A DISEASE IN AN ANIMAL IN WHICH THE ACTIVITY OF CYSTEINE PROTEASE CONTRIBUTES TO APATOLOGY AND / OR DISEASE SYMPTOMS IN A DISEASE AND A DISEASE SYMPTOMATOLOGY IN A DISEASE AND A DISEASE SYMPTOMS. ACTIVITY OF CATATEPSIN S CONTRIBUTES TO THE PATHOLOGY AND / OUSYTOMATOLOGY OF THE DISEASE ". The present invention relates to new N-cyanomethyl amides which are cysteine protease inhibitors, to the pharmaceutically acceptable salts and N-oxides thereof, to their uses as therapeutic agents and to the processes for their preparation.