Compound, methods of inhibiting biological effects of a deregulated protein-tyrosine kinase in a mammal needing it, treating, inhibiting the growth of, or eradicating neoplasms in a mammal needing it, treating, inhibiting the process of, or eradicating polycystic kidney disease and colonic polyps in a mammal needing it, and pharmaceutical composition

摘要

"COMPOUND, METHODS OF INHIBITING BIOLOGICAL EFFECTS OF A DREGULATED PROTEIN-THYROSINE-KINASE IN A MAMMALIAN NEEDING THE SAME, TREATING, INHIBITING THE GROWTH OF, OR ERADICATING NEOPLASMS IN A MAMMALIAN, NEEDING TO DEMISE, REQUIRING MISSING NEEDLES ERADICATE POLITICALLY DISEASE OF THE KIDNEYS AND COLLINIC POLLINES IN A MAMMALIAN NEEDING THE SAME, AND PHARMACEUTICAL COMPOSITION ". This invention provides compounds of formula (I) having structure (a) in which A "is a divalent group selected from the group (a, b, c) which are useful as protein tyrosine kinase inhibitors.