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Drug carrier for controlled administration of active ingredient, prepared from lipid-drug matrix conjugates (ldc particles)

机译:由脂质-药物基质结合物(ldc颗粒)制备的用于活性成分控制给药的药物载体

摘要

Invention Patent: "DRUG VEHICLE FOR CONTROLLED ADMINISTRATION OF ACTIVE INGREDIENT, PREPARED FROM DRUG MATRIX CONJUGATES (PARTICLES OF LDC)". The invention relates to vehicles of particulate active ingredients that are in the solid aggregate state at room temperature (20 198 C) and consist of a pure lipid-drug conjugate (LDC) or a mixture of several LDCs as a particle matrix, the LDC bond being made by covalent bonding, electrostatic interactions, dipolar moments, dispersion forces, ionic interactions, hydrogen bonds and / or hydrophobic interactions.
机译:发明专利:“由药物基质共轭物(LDC的颗粒)制得的用于控制活性成分控制的药物的车辆”。本发明涉及在室温(20 198℃)下为固体聚集状态的颗粒活性成分的载体,其由纯脂质-药物缀合物(LDC)或几种LDC的混合物作为颗粒基质组成, LDC键是通过共价键,静电相互作用,偶极矩,分散力,离子相互作用,氢键和/或疏水相互作用形成的。

著录项

  • 公开/公告号BR0010356A

    专利类型

  • 公开/公告日2002-02-13

    原文格式PDF

  • 申请/专利权人 PHARMASOL GMBH;

    申请/专利号BR20000010356

  • 发明设计人 RAINER HELMUT MUELLER;CARSTEN OLBRICH;

    申请日2000-05-08

  • 分类号A61K47/48;A61K47/44;A61K9/10;A61K9/14;A61K38/00;A61K31/19;

  • 国家 BR

  • 入库时间 2022-08-22 00:46:14

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