Method of treating thrombosis in a mammal, and using a combination of (i) a factor xa inhibitor, and (ii) a compound selected from the group consisting of aspirin, tpa, a gpiib / iiia antagonist, low weight heparin molecular and heparin

摘要

"METHOD OF TREATING THROMBOSIS IN A MAMMALIAN, AND USE OF A COMBINATION OF (I) A FACTOR XA INHIBITOR, AND (II) A SELECTED COMPOSITION OF THE GROUP THAT CONSISTS OF ASPIRIN, TPA, A GPIIB / IIIA ANTAGONIST, LOW HEPARINE MOLECULAR WEIGHT AND HEPARIN ". It is a method of treating thrombosis in mammals by administering therapeutically effective amounts of a combination of (i) a factor Xa inhibitor, and (ii) a compound selected from the group consisting of aspirin, a GPIIb / antagonist IIIa, low molecular weight heparin and heparin, and the dose administered to at least one of (i) and (ii) is a subtherapeutic dose. Preferably, the combination of (i) and (ii) provides a synergistic effect.