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Derivatives of phenylpropanoic acid substituted as alpha activated human proliferating peroxisome receptor (ppar) agonists

机译:苯基丙酸的衍生物被取代为α活化的人类增殖过氧化物酶体受体(ppar)激动剂

摘要

Invention Patent: "PHENYLPROPANOIC ACID DERIVATIVES REPLACED AS AGONISTS OF THE HUMAN ACTIVATED PROLIFERANT PEROXISOMA RECEPTOR (PPAR)". The invention provides new substituted phenylpropanoic acid derivatives that are activated by binding to a human activated proliferative peroxisome receptor (PPAR 244) ligand receptor and exhibit potent blood lipid lowering action (cholesterol and triglycerides). It refers to substituted phenylpropanoic acid derivatives represented by the general formula (1): their pharmaceutically acceptable salts and their hydrates and processes for preparing them.
机译:发明专利:“取代了人类活化的过氧化物酶体过氧化物受体(PPAR)的激动剂的苯丙酸衍生物”。本发明提供了新的取代的苯基丙酸衍生物,其通过与人活化的增殖性过氧化物酶体受体(PPAR <244>)配体受体结合而被活化,并表现出有效的降血脂作用(胆固醇和甘油三酸酯)。它是指由通式(1)表示的取代的苯基丙酸衍生物:它们的药学上可接受的盐和其水合物以及制备它们的方法。

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