首页> 外国专利> Photoactivable pharmaceutical composition for selective destruction and / or inactivation of immunologically reactive cells, use thereof, and methods for preventing graft-versus-host disease associated with allogeneic stem cell transplantation in a patient, for treatment of immune disorder in one patient and to assess the transport mechanism of immune and / or malignant cells

Photoactivable pharmaceutical composition for selective destruction and / or inactivation of immunologically reactive cells, use thereof, and methods for preventing graft-versus-host disease associated with allogeneic stem cell transplantation in a patient, for treatment of immune disorder in one patient and to assess the transport mechanism of immune and / or malignant cells

机译:用于选择性破坏和/或灭活免疫反应性细胞的光活化药物组合物,其用途以及在患者中预防与同种异体干细胞移植相关的移植物抗宿主病,在一名患者中治疗免疫紊乱并评估治疗方法免疫和/或恶性细胞的转运机制

摘要

"PHOTOACTIVABLE PHARMACEUTICAL COMPOSITION FOR SELECTIVE DESTRUCTION AND / OR INACTIVATION OF IMMUNOLOGICALLY REACTIVE CELLS, USE OF THE SAME, AND METHODS FOR THE PREVENTION OF EVERYTHING OF A GRAPHIC CONCERNATION OF EMERGED UNDERGROUND THERAPEUTIC ASSOCIATION OF TRICHESIS. A PATIENT AND TO EVALUATE THE MECHANISM FOR TRANSPORTING IMMUNE AND / OR MALIGNAL CELLS ". The present invention relates to the use of photoactivable derivatives for the photodynamic treatment for the selective destruction and / or inactivation of immunologically reactive cells, without affecting normal cells and without causing systemic toxicity to the patient, at which appropriate intracellular levels of said derivatives are achieved and radiation of an appropriate wavelength and intensity is applied.
机译:“用于选择性破坏和/或失活免疫反应性细胞的可光化药物组合物,使用该药物组合物,以及用于预防与治疗有关的,与治疗相关联的治疗方法的每一种图形化确认的方法和/或恶意细胞”。本发明涉及光活化衍生物在光动力学治疗中用于选择性破坏和/或失活免疫反应性细胞而不影响正常细胞和不对患者造成全身毒性的用途,在此可达到所述衍生物的适当细胞内水平并施加适当波长和强度的辐射。

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