Use of agents to improve penetration and break through skin barriers, improve the immune transcutaneous response induced by the adp ribosylation ethoxine

摘要

Invention Patent: "USE OF AGENTS TO IMPROVE PENETRATION AND BREAKAGE OF SKIN BARRIERS, TO IMPROVE THE IMMUNE TRANSCUTANEOUS RESPONSE INDUCED BY ADP RIBOSYLATING EXOTOXIN". The present invention comprises a transcutaneous immunization system, in which the topical application of a coadjuvant and an antigen or nucleic acid encoding an antigen to intact skin, induces a systemic or mucosal antibody response. The immune response thus deduced, can be improved through physical or chemical agents that improve skin penetration.