首页> 外国专利> Pharmaceutical composition comprising (a) a nicotine receptor partial agonist defined, (b) an inhibitor of acetyl or butilcolinesterasa, estrogenic Agent,An Estrogen Receptor Modulator or a agonsita Muscarinic and (c) a vehicle, useful for treating cognitive disorders such as Alzheimer's disease and schizophrenia.

Pharmaceutical composition comprising (a) a nicotine receptor partial agonist defined, (b) an inhibitor of acetyl or butilcolinesterasa, estrogenic Agent,An Estrogen Receptor Modulator or a agonsita Muscarinic and (c) a vehicle, useful for treating cognitive disorders such as Alzheimer's disease and schizophrenia.

机译:药物组合物,其包含(a)所定义的尼古丁受体部分激动剂,(b)乙酰基或丁二烯丙基酯抑制剂,雌激素剂,雌激素受体调节剂或激动性毒蕈碱和(c)运载体,其用于治疗认知障碍例如阿尔茨海默氏病和精神分裂症。

摘要

A Pharmaceutical composition useful in the treatment of Cognitive dysfunction in a Mammal, which contains an inhibitor of acetylcholinesterase,An inhibitor of an agent butilcolinesterasa, estrogen, Selective Estrogen Receptor Modulator or a Muscarinic agonist.Or a pharmaceutically acceptable Salt thereof; and a pharmaceutically acceptable vehicle.The partial agonist nicotine of the receiver and the inhibitor of acetylcholinesterase, inhibitor butilcolinesterasa, estrogenThe Selective Estrogen Receptor Modulator or the Muscarinic agonist are present in quantities that make the effective composition in the potentiation of the Cognition and TreatmentCognitive dysfunction and diseases including, but without imitation, Alzheimer's disease, mild cognitive impairment, age-related Cognitive decline.Vascular dementia, dementia, Parkinson's disease, Huntington's disease, Stroke, bits associated with AIDS Dementia and schizophrenia.
机译:用于治疗哺乳动物的认知功能障碍的药物组合物,其包含乙酰胆碱酯酶抑制剂,butilcolinesterasa剂,雌激素,选择性雌激素受体调节剂或毒蕈碱激动剂的抑制剂。受体的部分激动剂烟碱和乙酰胆碱酯酶的抑制剂,抑制剂butilcolinesterasa,雌激素选择性雌激素受体调节剂或毒蕈碱激动剂的存在量可有效增强认知和治疗的功能,认知功能障碍和疾病,包括但不模仿为阿尔茨海默氏病,轻度认知障碍,与年龄有关的认知能力下降,血管性痴呆,痴呆,帕金森氏病,亨廷顿舞蹈病,中风,与艾滋病相关的痴呆和精神分裂症。

著录项

  • 公开/公告号CL2001000987A1

    专利类型

  • 公开/公告日2002-01-14

    原文格式PDF

  • 申请/专利权人 PFIZER PRODUCTS INC.;

    申请/专利号CL2001000987

  • 申请日2001-04-30

  • 分类号A61K31/00;A61K45/06;A61P25/28;

  • 国家 CL

  • 入库时间 2022-08-22 00:45:56

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