Fenilaminas cyclic Derivatives, and their salts, Pharmaceutical composition useful, useful as Beta 3 adrenergic receptor agonists to treat insulin resistance or hyperglycemiaType II diabetes, urinary incontinence, atherosclerosis, gastrointestinal disorders, neurogenetic inflammation, glaucoma, ocular hypertension.

摘要

The present Invention relates to compounds of the formula I with the structure where R1, R2, R3, R4, R5, T, T2,And x are defined in the Claims, or a pharmaceutically acceptable Salt thereof,Which are appropriate in the Treatment or inhibition of desrodenes Related Metabolic insulin resistance or hyperglycemia (typically associated with Obesity or intolerableSo the arteriosclerosis Glucose), gastrointestinal disorders, neurogenetic inflammation, glaucoma,Ocular hypertension or frequent urination and are particularly appropriate in the Treatment or inhibition of Type II diabetes.