首页> 外国专利> Use of 1 - 4 - (5 - cianoindol - 3 - il) butyl - 4 - (2 - carbamoyl - benzofuran - 5 - yl) - piperazine or 3 - (4 - 4 - (Cyano phenyl) piperazin-1-yl butyl - 1H indole - 5 - carbonitrilo or acceptable salts thereof,To prepare a drug used in the treatment of diseases, in particular, the irritable bowel syndrome.

Use of 1 - 4 - (5 - cianoindol - 3 - il) butyl - 4 - (2 - carbamoyl - benzofuran - 5 - yl) - piperazine or 3 - (4 - 4 - (Cyano phenyl) piperazin-1-yl butyl - 1H indole - 5 - carbonitrilo or acceptable salts thereof,To prepare a drug used in the treatment of diseases, in particular, the irritable bowel syndrome.

机译:使用1-[4-(5-佳乐宁吲哚-3-il)丁基]-4-(2-氨基甲酰基-苯并呋喃-5-yl)-哌嗪或3-(4-[4-(氰基苯基)哌嗪-1] [-基]丁基] -1H吲哚-5-碳三腈或其可接受的盐,用于制备用于治疗疾病,特别是肠易激综合症的药物。

摘要

Use of compounds that consist of combinations of selective serotonin reuptake inhibitors (SSRIs) (5HT) and 5-ht1a receptor agonists.In particular, 1 - (5 - (5 - cianoindol - 3 - il) butyl) - 4 - (2 - carbamoyl - benzofuran - 5 - yl) - piperazine or A physiologically acceptable Salt thereof or3 - (4 - (4 - (Cyano phenyl) - (piperazin-1-yl) - Butyl) - 1H indole - 5 - carbonitrilo or A physiologically acceptable Salt thereof,For the preparation of a Medicament for the treatment of chronic disorders with color or in the treatment of other conditions in which there is a hypersensitization to meanS Pain, hyperalgesia, allodynia, increased perception of Pain and increased Pain Memory.
机译:由选择性5-羟色胺再摄取抑制剂(SSRIs)(5HT)和5-ht1a受体激动剂的组合组成的化合物的使用,尤其是1-(5-(5--cianoindol-3-il)丁基)-4-(2-氨基甲酰基-苯并呋喃-5-基)-哌嗪或其生理上可接受的盐或3-(4-(4--(氰基苯基)-(哌嗪-1-基)-丁基)-1H吲哚-5-碳腈或生理上可接受的盐其盐,用于制备用于治疗具有颜色的慢性疾病或用于治疗其他疾病的药物,在这些疾病中,超敏性表示疼痛,痛觉过敏,异常性疼痛,疼痛感增强和疼痛记忆增强。

著录项

  • 公开/公告号CL2001002798A1

    专利类型

  • 公开/公告日2002-07-22

    原文格式PDF

  • 申请/专利权人 MERCK PATENT GMBH;

    申请/专利号CL2001002798

  • 发明设计人 BARTSOZYK GERD;SEDMAN EWEN;

    申请日2001-11-19

  • 分类号A61K31/00;A61K31/496;A61P1/00;A61P29/00;

  • 国家 CL

  • 入库时间 2022-08-22 00:45:53

相似文献

  • 专利
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号