首页> 外国专利> Organic Compounds are inhibitors of cysteine proteases, particularly cathepsin K inhibitors of arilaminoalquilamida,And its pharmaceutical use for the Treatment or prophylaxis of diseases or medical conditions in which this involved

Organic Compounds are inhibitors of cysteine proteases, particularly cathepsin K inhibitors of arilaminoalquilamida,And its pharmaceutical use for the Treatment or prophylaxis of diseases or medical conditions in which this involved

机译:有机化合物是半胱氨酸蛋白酶的抑制剂,尤其是阿立氨基酰胺酶的组织蛋白酶K抑制剂,及其在治疗或预防其中涉及的疾病或医学状况方面的药物用途

摘要

The invention relates to an amino acid - arilaminolequilamidia, in which the C-terminal group of amino acid is replaced by an alternative of arilaminolequilamino, There, the nitrogen atom of the amino acid forms a link to a peptide or pseudo peptide, in which an alternative can of a meta heteroatom is added,Or an additional heteroatom, which is directly replaced by arilo, low tar, low tar, low tar or isomerized atom. In its next word, it defines a compound or an excimer, which can be diffused or undiffusion with up to and including seven carbon atoms or a physical ester. Acceptable, separable, or salt.
机译:本发明涉及一种氨基酸-阿立氨酰氨基阿米巴胺,其中氨基酸的C-末端基团被另一种阿立氨酰氨基阿胺基氨基取代,其中氨基酸的氮原子形成与肽或假肽的连接,其中添加间杂原子的替代罐,或另外的杂原子,其直接被arilo,低焦油,低焦油,低焦油或异构原子取代。用它的下一个词,它定义了一种化合物或准分子,可以扩散或不扩散,最多包含七个碳原子或一种物理酯。可接受,可分离或含盐。

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