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Process for obtaining a liquid extract of shark cartilage, the cartilage extract obtained in such a process and compositions containing such cartilage extract and their use

机译:获得鲨鱼软骨的液体提取物的方法,以这种方法获得的软骨提取物以及含有这种软骨提取物的组合物及其用途

摘要

In the present invention there is disclosed a process for obtaining a liquid extract of shark cartilage, which process is characterized in that it comprises the following steps: a) homogenizing pieces of solid shark cartilage in a non-denaturing aqueous solution until said pieces of solid shark cartilage are reduced to solid particles whose size is lower than or equal to about 500 micrometers, resulting in a mixture of said solid particles and a crude liquid extract; b) separating said crude liquid extract from said solid particles; and c) further separating the crude liquid extract so as to obtain a final liquid extract containing cartilage molecules having a molecular weight lower than or equal to 500 000. The invention also relates to a cartilage extract being prepared by the above-described process, further compositions for treating dermatological disorders or diseases, containing a therapeutically effective amount of the cartilage extract in connection with a pharmaceutically acceptable vehicle. The invention further relates to a topic composition for treating psoriasis or acne as well as composition for treating cancer.
机译:在本发明中,公开了一种获得鲨鱼软骨的液体提取物的方法,该方法的特征在于它包括以下步骤:a)在非变性水溶液中均化固体鲨鱼软骨的碎片,直到所述固体碎片将鲨鱼软骨还原成尺寸小于或等于约500微米的固体颗粒,从而形成所述固体颗粒和粗制液体提取物的混合物; b)从所述固体颗粒中分离出所述粗液体提取物; c)进一步分离粗制液体提取物以获得含有分子量小于或等于500000的软骨分子的最终液体提取物。本发明还涉及通过上述方法制备的软骨提取物,进一步用于治疗皮肤病或疾病的组合物,其包含治疗有效量的软骨提取物以及药学上可接受的载体。本发明进一步涉及用于治疗牛皮癣或痤疮的主题组合物以及用于治疗癌症的组合物。

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