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Use of nitric oxide synthase substrate and / or donor or nitric oxide inhibitor for the manufacture of medicaments for the treatment of uterine contact disorders
Use of nitric oxide synthase substrate and / or donor or nitric oxide inhibitor for the manufacture of medicaments for the treatment of uterine contact disorders
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机译:一氧化氮合酶底物和/或供体或一氧化氮抑制剂在制备用于治疗子宫接触障碍的药物中的用途
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摘要
Dysmenorrhea, disfunctional uterine bleeding, preterm labor and postpartum labor in female mammals are treated by inhibiting uterine contractility by administering thereto a nitric oxide synthase substrate, a nitric oxide donor or both, optionally in combination with one or more of a prostaglandin inhibitor, a prostacyclin-mimetic, a progestin, an oxytocin antagonist or a beta -agonist in an amount effective to ameliorate the symptoms thereof; and inadequate menses treated and induction of abortion or stimulation of labor in a pregnant female is achieved by uterine contractility stimulation by administering thereto a nitric oxide inhibitor, either alone or in a combination of progesterone antagonist, an oxytocin or oxytocin analogue antagonist or prostaglandin.
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