new substituted azetidinones as anti-inflammatory agents and anti degeneration.

摘要

Substituted azetidinones of the general Formula (I) which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents, CHEM wherein R4 is (a) CHEM b) CHEM where Rx is carboxy C1-6alkyl, benzyloxycarbonylC1-3alkyl, or t-butoxycarbonylC1-3alkyl, wherein Q is a covalent bond or CHEM Y is CHEM or CHEM or a covalent bond.