THE USE OF GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR FAMILY-RELATED COMPOUNDS FOR REGULATING SPERMATOGENESIS AND FOR PREPARING MALE CONTRACEPTIVES

摘要

The present invention relates to compounds of the glial cell line neurotrophic factor (GDNF) family, namely glial cell line neurotrophic factor (GDNF), GDNF-like factors such as apersephin, artemin and neurturin, or other compounds that have a signal transducing receptor, cRet receptor tyrosine. kinase and / or coreceptors, such as the GDNF family receptor α: s (GFRα1-4), act similarly to GDNFs and are used for the regulation and study of aspermatogenesis, for the inhibition of sperm differentiation, for the development of male contraceptives and for their use. SHE