Vaccines for the prevention of clostridial diseases of sheep that provide effective immunity for up to a year or more from a single dose

摘要

Described are vaccines suitable for the prevention of Clostridial diseases of sheep (and lambs), providing an effective immunity for up to a year or more following a single injection or dose. The sheep vaccine composition comprises: an oily adjuvant acceptable for veterinary purposes comprising: i) a white mineral oil having a molecular weight of about 250 to 300 and ii) a mannitol oleate emulsifier and an aqueous phase comprising one or more Clostridial antigens selected from the group consisting of Clostridium periiringens type A, B, C and D, Clostridium septicum, Clostridium tetani, Clostridium chauvoei, Clostridium novyi type B, Clostridium sordelli, Clostridium haemolyticum and Clostridium botulinium C and D.