首页> 外国专利> 3 - Chloro - 5 - (4 - metansulfonilfenilo) - 6 - methyl - 2,3 bipiridinilo in Pure Crystalline form and Process for Synthesis

3 - Chloro - 5 - (4 - metansulfonilfenilo) - 6 - methyl - 2,3 bipiridinilo in Pure Crystalline form and Process for Synthesis

机译:纯结晶形式的3-氯-5-(4-甲磺酰芬尼洛)-6-甲基-[2,3]双哌啶子诺及其合成方法

摘要

Refers to a Polymorph of Chloro - 5 - 3 - (4 - metansulfonilfenilo) - 6 - methyl - [2,3] bipiridinilo 'formula (V), (etoricoxib), characterised by its x-ray diffraction pattern.CU K Alpha approximately 13.7 Au00b0, initial Melting Point of 133.9u00b0c by Differential Scanning Calorimetry (CED) and Melting Point end of 134.5u00b0c by CED.Compound i Inhibits Cyclooxygenase 2 and may be useful for the treatment of inflammatory disease sensitive to treatment with an anti-inflammatory steroid such as Rheumatic Fever,Symptoms of the flu, common cold, back pain, neck pain, dysmenorrhea, headache, Tooth Pain, Sprains, strains, bursitis, arthritis, myositis, Burns
机译:指氯-5-3-(4-甲磺砜基芬尼洛)-6-甲基-[2,3]双哌啶酮'式(V),(etoricoxib)的多晶型物,特征在于其X射线衍射图.CU K Alpha大约13.7 A u00b0,差示扫描量热法(CED)的初始熔点为133.9 u00b0c,CED的熔点终点为134.5 u00b0c。化合物i抑制环加氧酶2,可能对治疗敏感的炎症疾病有用。抗炎类固醇,例如风湿热,流感症状,普通感冒,背部疼痛,颈部疼痛,痛经,头痛,牙痛,扭伤,拉伤,滑囊炎,关节炎,肌炎,烧伤

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