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peptide capable of inhibiting the activity of platelet derived growth factor (pdgf bb) and growth factor derived from fi
peptide capable of inhibiting the activity of platelet derived growth factor (pdgf bb) and growth factor derived from fi
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机译:能够抑制血小板衍生生长因子(pdgf bb)和衍生自fi的生长因子活性的肽
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摘要
A novel peptide, derived from the human fibroblast growth factor (bFGF), is identified. The molecule is able to inhibit in vitro the effects of Platelet Derived Growth Factor (PDGF-BB) and basic Fibroblast Growth Factor (bFGF) on primary rat smooth muscle cells (RASMC) and primary bovine endothelial cells (BAEC) The molecule is also able to inhibit in vivo angiogenesis CD1 mice.
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