USE OF TERFENADINE DERIVATIVES AS ANTIHISTAMINICS IN A PATIENT WHO HAS HEPATIC DISORDERS.

摘要

THE PRESENT INVENTION REFERS TO A METHOD FOR PROVIDING AN ANTIHISTAMINAL EFFECT IN A HEPATICALLY DAMAGED PATIENT THAT NEEDS IT, AND THAT CONSISTS IN MANAGING SUCH PATIENT AN EFFECTIVE ANTIHISTAMINAL AMOUNT OF A FORMULA I ORIGINAL FORM (1) HYDROXY; R2 IS HYDROGEN; OR R1 AND R2 TOGETHER FORM A SECOND LINK BETWEEN CARBON ATOMS THAT CARRY R1 AND R2; N IS A BETWEEN 1 TO 5; R3 IS -COOH OR -COOALKILO WHERE THE ALKILO UNIT HAS 1 TO 6 CARBON ATOMS AND IS OF A STRAIGHT OR BRANCHED CHAIN; EACH A AND B IS HYDROGEN OR HYDROXY ALWAYS AND WHEN AT LEAST ONE BETWEEN A AND B IS HYDROGEN; OR A PHARMACEUTICALLY ACCEPTABLE SALT AND INDIVIDUAL ISOMERS OF THE SAME.