TRIACETINE AS IMPROVER OF TRANSDERMAL PENETRATION.

摘要

A COMPOSITION AND A PROCEDURE TO INCREASE THE TRANSDERMAL PENETRATION OF A BASIC PHARMACO IS DESCRIBED. THE COMPOSITION INCLUDES A MATRIX PATCH THAT INCLUDES AN EFFECTIVE AMOUNT OF A BASIC PHARMACO, THAT PREFERIBLY PRESENTS A PK A OF APPROXIMATELY 8.0 OR GREATER, AN EFFICIENT AMOUNT OF A PENETRATION POTENTIATOR THAT CONSENTS ESSENTIALLY IN ONE AND THREE POLYMER THAT PREFERIBLY INCLUDES A PIEZOSENSIBLE ADHESIVE. A PREFERRED BASIC PHARMACO IS OXIBUTININE AND THE ACID ADDITION SALTS OF THE SAME. THE PROCEDURE TO INCREASE TRANSDERMAL PENETRATION INCLUDES APPLYING THE MATRIX PATCH TO A SELECTED SKIN AREA.