THE USE OF ISOLATED DOMAINS OF TYPE IV COLLAGEN TO MODIFY THE INTERACTIONS OF CELLS AND FABRICS.

摘要

THE PRESENT INVENTION SHOWS THAT THE 7S DOMAIN OF THE TYPE IV COLLAGEN BREAKS THE CELLULAR AGGREGATION AND THE DEVELOPMENT OF THE FABRICS. THE STRUCTURAL CHANGES IN THE MESOGLE, THE INHIBITION OF THE CELL PROLIFERATION AND CHANGES IN THE CELL DIFFERENTIATION PATTERNS THAT ACCOMPANY THE LOCK OF THE CELLULAR AGGREGATES THAT INDICATE THAT THE BLOCK CAN BE DUE TO ALTERATION IN THE MATTER EXTRACTION (EXTENSION) ADJECTIVE EFFECTS ON CELLULAR BEHAVIOR. THE TYPE IV COLLAGEN PLAYS A BASIC ROLE IN THE INITIAL FORMATION OF THE MESOGLE, AFFECTING THE MESOGLE FORMATION TO THE CELL DIVISION, CELL DIFFERENTIATION AND MORPHOGENESIS.