REGULATORY SEQUENCES OF THE GEN CD4 AND ITS SPECIFIC EXPRESSION IN THE MATURE T LYMPHOCYTES.

摘要

EXPRESSION SYSTEM OF A PROTEIN OR A HETEROLOGICAL GENE THAT INCLUDES A RECOMBINING VECTOR, USED FOR THE TRANSDUCTION OF CELLS OF THE HEMATOPOYETIC SERIES, MAINLY OF MOTHER CELLS, SUCH WAY THAT THE CELL MAKES THEM PROPRESSED BY IT LINFOCITOS T MATUROS PRIOR SELECTION OF THE REPERTORY. THE RECOMBINING VECTOR IS PROVIDED WITH ALL THE SEQUENCES THAT IT NEEDS TO EXPRESS HIM AND IS CHARACTERIZED BY THE FACT THAT IT CONTAINS AT LEAST AN AMPLIFIER OF A GENE CD4 OF THE SAME SPECIES OR OF A DIFFERENT SPECIES.