首页> 外国专利> Process for the preparation of pharmaceutical compounds by complexing drug reservoir comprising cyclodextrins on inert or active cores.

Process for the preparation of pharmaceutical compounds by complexing drug reservoir comprising cyclodextrins on inert or active cores.

机译:通过在惰性或活性核上络合包含环糊精的药物储库来制备药物化合物的方法。

摘要

The object of this invention is a process for preparing pharmaceutical compositions consist of a core inert or active IN deposited a complex of a drug and cyclodextrin. This complex is basically the preparation of a constituent in the liquid phase, comprising a NATURAL SOLUTION OR MODIFIED cyclodextrin in a solvent or solvent mixture PROPER DISSOLUTION OF A CERTAIN AMOUNT OF MEDICATION AND THE SOLUTION AND FINALLY, IN THE PREPARATION A second liquid phase consisting essentially of a solution or suspension of a polymer in the solvent SAME. STAGES TO COMBINE BOTH obtained immediately a solution or suspension DISPERSA COMPLEX Drug-cyclodextrin polymer. The solution or slurry is sprayed on inert cores or ASSETS AND SIMULTANEOUSLY his solvent by evaporation, siltation TO OBTAIN COMPOUND IN ASSETS OR Inert cores.
机译:本发明的目的是一种制备药物组合物的方法,该药物组合物由核心惰性或活性IN沉积的药物和环糊精的复合物组成。该配合物基本上是在液相中制备的一种成分,包括在溶剂或溶剂混合物中的天然溶液或改性环糊精。一定剂量的药物的正确溶解以及制备中的溶液和最终制剂第二种液相基本上由聚合物在溶剂SAME中的溶液或悬浮液的制备。合并阶段均可立即获得溶液或悬浮液DISPERSA COMPLEX药物-环糊精聚合物。将溶液或浆液喷洒在惰性芯或资产上,并通过蒸发,淤积将其溶剂同时沉淀成资产或惰性芯中的化合物。

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