NEW METHOD OF DOSAGE OF HYDROXOCOBALAMINE AND ITS USE IN THE CYANIDE POISONING.

摘要

THE INVENTION REFERRES TO THE PHARMACEUTICAL FIELD, AND MORE SPECIALLY TO THERAPEUTIC CHEMISTRY. REFERENCE IS MADE TO A NEW FORM OF DOSAGE OF HYDROXOCOBALAMINE THAT IS USEFUL IN THE TREATMENT OF CYANIDE POISONING. THE NEW PHARMACEUTICAL COMPOSITIONS IN ACCORDANCE WITH THE INVENTION CONTAIN DRY HYDROXOCOBALAMINE IN A FREEZING POINT. HYDROXOCABALAMINE IS DRIED AT FREEZING POINT IN AN ACIDIC ENVIRONMENT TO BE PRACTICALLY REDISELTED INSTANTLY IN A NEUTRAL SALT SOLUTION. THIS INVENTION ALSO REFERS TO A PROCESS TO PRODUCE HYDROXOCOBALAMINE BASED PHARMACEUTICAL COMPOSITIONS AS WELL AS THE FIRST HELP TEAM CONTAINING THESE COMPOSITIONS. IT IS USED FOR THE TREATMENT OF POISONING BY CIANIDA.