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ANTI-STRESS, ANTI-IMPAIRMENT AND ANTI-AGING DRUG AND PROCESS FOR MANUFACTURING THEREOF

机译:抗应力,抗损伤和抗老化药物及其制造方法

摘要

The invention relates to a new pharmacotherapeutical strategy, to an anti-stress, anti-impairment and anti-aging drug and to a process for itsmanufacturing. The drug has an etio-pathogenic and homeostatic action, waspreclinically tested and clinically checked up in geriatric, neurologic,psychiatric and stress-dependent pathology. The drug achieves a synergisticbiological, neurometabolic and cell-trophic composition, being elaborated bythe association of the following active principles: a) against oxidative andcatabolic stress: methionine with aminoethanol phenoxyacetates and/oraminoethyl phenoxyacetamides; b) against anabolic stress: hydrooxopyrimidinecarboxylates and/or oxopyrrolidine acetamides with potassium, zinc andlithium; c) vasodilative and normolipidemic: nicotinic, alcohol and/or acid,or its derivatives, with magnesium and iodine; d) energo-active and e) anti-toxic: aspartate; fructose; vitamin B1; vitamin B6; monoacid phosphate andsulfate. The process for manufacturing the drug stipulates: a) pharmaceuticalpreparation in two complementary types of capsules or coated tablets,gastrosoluble and enterosoluble, the last being enteric coated; b) prolonged-release of vasodilator from the enterosoluble unit.
机译:本发明涉及新的药物治疗策略,涉及抗压力,抗损伤和抗衰老药物及其制造工艺制造业。该药物具有致病性和体内稳态作用,在老年,神经系统,精神病和压力依赖性病理。该药具有协同作用生物学,神经代谢和细胞营养组成,由以下有效原则的关联:a)抗氧化和分解应激:蛋氨酸与氨基乙醇苯氧乙酸盐和/或氨乙基苯氧基乙酰胺; b)对抗同化应激:氢氧嘧啶羧酸盐和/或氧吡咯烷乙酰胺与钾,锌和锂; c)血管扩张和降血脂:烟碱,酒精和/或酸,或其衍生物与镁和碘; d)激发能量,e)反有毒的;天门冬氨酸;果糖;维生素B1;维生素B6;磷酸一酸和硫酸盐。制造药物的过程规定:a)制药有两种互补的胶囊或包衣片剂形式的制剂,胃溶性和肠溶性,最后被肠溶衣; b)延长─从肠溶性单位释放血管扩张剂。

著录项

  • 公开/公告号CA2191837C

    专利类型

  • 公开/公告日2002-10-15

    原文格式PDF

  • 申请/专利权人 RIGA DAN;RIGA SORIN;

    申请/专利号CA19942191837

  • 发明设计人 RIGA DAN;RIGA SORIN;

    申请日1994-06-02

  • 分类号A61K45/06;

  • 国家 CA

  • 入库时间 2022-08-22 00:41:17

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