A novel polypeptide-human dna-dependent rna polymerase ac40 subunit inhibitor 9.13 and the polynucleotide encoding said polypeptide

摘要

The invention discloses a new polypeptide-human DNA-dependent RNA polymerase AC40 subunit inhibitor 9.13, the polynucleotide encoding said polypeptide, and a process for producing the polypeptide by recombinant DNA technology. It also discloses methods of applying the polypeptide for the treatment of various diseases, such as fetation abnormality, tumor, and protein metabolism disorder disease. This invention also discloses antagonist against said polypeptide and thereof therapy uses. In addition, it refers to the use of said polynucleotide encoding this new human DNA-dependent RNA polymerase AC40 subunit inhibitor 9.13.