5,10,15,20-tetra(hydroxyphenyl)porphyrins in cancer treatment

摘要

This invention provides novel compounds for therapy of tumours suceptible to necrosis when an appropriate compound is adminstered followed by illumination with light of a wavelength absorbed by the compound, the compounds being dihydro porphyrins of the formula, or the corresponding tetra-hydro porphyrins: CHEM where n = 1 to 3 and each substituent R, the same or different and at the same or different position in its respective substituent phenyl ring, is an hydroxy group.